Dr. Jarlenski and her team evaluated whether cannabis use was associated with nausea and vomiting in early pregnancy, and found that higher THC levels were associated with increased odds of moderate-to-severe nausea (20.7% THC detected vs 15.5% in THC not detected).
![Descriptive survey data from the Pregnancy-Unique Quantification of Emesis (PUQE) tool for the total PUQE score (A) and components of PUQE score (hours of nausea [B], episodes of vomiting [C], and episodes of dry heaves [D]) among those with and without detectable urine 11-nor-9-carboxy-delta-9-tetrahydrocannabinol (THC-COOH). The PUQE score evaluates symptoms over the previous 12 hours. E. Logistic regression model results for the association between THC-COOH and the primary outcome.](/sites/default/files/styles/large/public/2023-01/Screenshot%202023-01-06%20at%2011.39.49%20AM.png?itok=k-PkqbVf)